Trifluoroacetic Acid (TFA)

Product Introduction

Trifluoroacetic acid (TFA) is an important fluorinated organic strong acid with the molecular formula C₂HF₃O₂. As a key raw material for organic synthesis, pharmaceuticals, pesticides, and fluorinated materials production, TFA is widely used as a catalyst, solvent, and fluorinating agent due to its strong acidity, strong electron-withdrawing trifluoromethyl effect, and excellent solvent properties. It is applied in the fields of pharmaceuticals, pesticides, biomedical analysis, and high-end new materials.

Basic Information

Product Name: Trifluoroacetic Acid (TFA)

English name: Trifluoroacetic Acid

CAS No.: 76-05-1

Molecular formula: C₂HF₃O₂

Molecular weight: 114.02

EINECS No.: 200-929-3

Structural formula:

Product Advantages

- Strong acid catalytic performance: pKa value is 0.23, and its acidity is about 100,000 times stronger than that of acetic acid. It is widely used as a highly efficient catalyst in alkylation, acylation and polymerization reactions.

- Excellent solvent properties: It is miscible with water, alcohols, ethers and a variety of organic solvents, making it an ideal medium for fluorination, nitration and halogenation reactions.

- High purity and batch stability: The purity of the standard product is not less than 99.5%, and the impurity content is extremely low, meeting the requirements of precision synthesis and pharmaceutical production.

- Key reagents for pharmaceutical synthesis: Widely used in the deprotection of t-BOC groups in peptide synthesis, and is an important raw material for the production of GLP-1 class peptide drugs.

Industry Applications

Used as a pharmaceutical and pesticide intermediate, biochemical reagent, and organic synthesis reagent. Used in the synthesis of fluorinated compounds, pesticides, and dyes. A catalyst for esterification and condensation reactions; a protecting agent for hydroxyl and amino groups, used in the synthesis of sugars and peptides. Also used as a mineral processing agent. Used in organic synthesis.

Technical indicators

Why choose our products?

- Strict quality control system, complete batch test reports

- High purity (≥99.5%) and batch stability guaranteed

- Meets HG/T 2770-2006 standard, reliable quality.

- Continuous and stable supply capacity, supporting customized packaging

- Extensive experience in serving international markets

- Support product development and technical consulting

Packaging and Storage

Packaging specifications: 250kg all-plastic drum/plastic-lined steel drum. Store in a cool, dry, and well-ventilated place, keep the packaging sealed, and keep away from alkaline substances, oxidants, and food and animal feed. Equipped with corrosion-resistant packaging to ensure safe transportation and storage.

FAQ

Q1: What is trifluoroacetic acid mainly used for?

A: Primarily used as a deprotection agent in organic synthesis, pharmaceutical and pesticide intermediate production, and polypeptide synthesis.

Q2: Why is trifluoroacetic acid an important raw material for pharmaceutical synthesis?

A: Its trifluoromethyl structure and strong acidity make it a key reagent for t-BOC deprotection in peptide drug synthesis and it is widely used in the synthesis of various pharmaceutical intermediates.

Q3: What is the purity of the product?

A: The purity of the standard product is not less than 99.5%, and the moisture content is not higher than 0.1%.

Q4: Which industries is it suitable for?

A: Pharmaceutical, pesticide, biomedical analysis, organic synthesis and new materials research and development industries.

Q5: How to store it?

A: It is recommended to store in a sealed container in a cool, dry, and well-ventilated environment, away from alkalis and oxidizers, and avoid storing with food or feed.