4-Fluorobenzotrifluoride CAS 352-21-4, for Fluorinated Fine Chemicals, Pharmaceutical Intermediates, and Pesticide Intermediates Applications

1. Product Overview

4-Fluorobenzotrifluoride is an important fluorinated aromatic compound, belonging to the category of fluorinated trifluoromethylbenzene fine chemicals.

This product contains both a fluorine atom and a trifluoromethyl (CF₃) group in its molecular structure, offering good chemical stability, electron-modulating capability, and hydrophobic properties. It serves as an important basic raw material in fluorinated pharmaceuticals, pesticides, fine chemicals, and specialty materials research and development.

2. Product Specifications

Product Name: 4-Fluorobenzotrifluoride

English Name: 4-Fluorobenzotrifluoride

CAS No.: 352-21-4

Product Category: Fluorinated Aromatic Compound / Fine Chemical Intermediate

Structural Type: Para-Fluorinated Trifluoromethylbenzene

Application Areas: Pharmaceutical Intermediates, Pesticide Intermediates, Fluorinated Material Synthesis

3. Product Structural Characteristics

① Trifluoromethyl (CF₃) Structure

The CF₃ group enhances molecular electron-withdrawing capability, hydrophobic properties, and chemical stability, serving as an important functional structure in modern fluorinated chemicals.

② Fluoro Substituent Structure

The fluorine atom modulates aromatic ring electronic properties, enhances molecular performance, and provides space for subsequent chemical transformations.

③ Para-Substitution Structure

The symmetrical aromatic structure facilitates use as a stable synthetic building block in fine chemical applications.

4. Main Application Areas

① Fluorinated Pharmaceutical Intermediates

Used in fluorinated drug structure design and aromatic intermediate synthesis.

② Pesticide Intermediates

Used in the research and development of fluorinated herbicides, insecticides, and plant protection products.

③ Fine Chemical Synthesis

Serves as an important fluorinated aromatic raw material for further functional group transformations and complex molecule construction.

④ Fluorinated Materials Research & Development

Used in the study of functional chemicals, specialty materials, and fluorinated polymers.

5. Product Characteristics and Advantages

① Stable Structure with Broad Application Range

The combination of aromatic ring and CF₃ structure provides good chemical stability.

② High Fluorinated Value

The CF₃ and F elements together confer high added value.

③ Flexible Synthesis Applications

Can serve as an important starting material for various fluorinated aromatic compounds.

6. Distinctions from Related Products

① 4-Fluorobenzotrifluoride vs. Benzotrifluoride

Benzotrifluoride is a basic fluorinated aromatic raw material; 4-fluorobenzotrifluoride has an additional fluorine substituent, offering higher electronic properties and application value.

② 4-Fluorobenzotrifluoride vs. 1,4-Bis(trifluoromethyl)benzene

4-Fluorobenzotrifluoride contains one CF₃ and one F structure; 1,4-bis(trifluoromethyl)benzene contains two CF₃ structures, with different fluorine content and application directions.

③ 4-Fluorobenzotrifluoride vs. Other Halogenated Trifluoromethylbenzenes

Different halogen substitution positions affect subsequent reaction routes and application areas.

7. Russian Market Procurement Considerations

Customers typically focus on the following:

-GC Purity;

-Moisture Content;

-Single Impurity Control;

-Appearance and Color;

-Packaging Stability;

-Technical Documentation including COA, TDS, SDS;

-Long-Term Supply Capability.

8. Product Supply Advantages

-Fluorinated Aromatic Product Supply Capability;

-Supports International Customer Procurement Requirements;

-Provides Quality Documentation and Technical Data;

-Serves Pharmaceutical, Agrochemical, and Fine Chemical Industry Chain Customers.

9. Frequently Asked Questions (FAQ)

Q: What are the main applications of 4-Fluorobenzotrifluoride?

A: It is mainly used in fluorinated pharmaceutical intermediates, pesticide intermediates, and fine chemical synthesis.

Q: Why is the CF₃ structure important?

A: The CF₃ group improves molecular electronic properties, stability, and hydrophobicity, serving as an important structural unit in modern fluorinated chemicals.

Q: What documentation is typically required for procurement of this product?

A: COA, TDS, SDS, packaging information, and shipping documentation are typically required.