5-Bromo-2-fluorobenzotrifluoride CAS 367-22-6, for Fluorinated Pharmaceutical Intermediates, Pesticide Intermediates, and Fine Chemical Synthesis Applications

1. Product Overview

5-Bromo-2-fluorobenzotrifluoride is an important fluorinated aromatic fine chemical, belonging to the category of halogenated trifluoromethylbenzene high-value organic intermediates.

This product contains bromine, fluorine, and trifluoromethyl (CF₃) groups in its molecular structure, combining halogen reactivity with fluorinated structural stability. It serves as an important aromatic building block in pharmaceuticals, pesticides, electronic chemicals, and specialty organic synthesis.

2. Product Specifications

Product Name: 5-Bromo-2-fluorobenzotrifluoride

English Name: 5-Bromo-2-fluorobenzotrifluoride

CAS No.: 367-22-6

Product Category: Fluorinated Aromatic Compound / Fine Chemical Intermediate

Molecular Type: Brominated Fluorinated Trifluoromethylbenzene

Application Areas: Pharmaceutical Intermediates, Pesticide Intermediates, Custom Organic Synthesis

3. Product Structural Characteristics

① Trifluoromethyl (CF₃) Structure

The CF₃ group enhances molecular electron-withdrawing capability, hydrophobicity, and chemical stability, serving as an important structural unit in modern fluorinated pharmaceuticals and agrochemicals.

② Bromine Substituent Structure

The bromine atom offers good reactivity for further construction of complex aromatic molecules through Suzuki coupling, palladium-catalyzed coupling, and other reactions.

③ Fluorine Substituent Structure

The fluorine atom modulates molecular electronic effects, enhancing the performance and application value of target compounds.

4. Main Application Areas

① Fluorinated Pharmaceutical Intermediates

Used in fluorinated drug molecule design and aromatic structure construction, serving as an important synthetic building block in pharmaceutical research and development.

② Pesticide Intermediates

Used in the development of fluorinated herbicides, insecticides, and plant protection products.

③ Fine Chemical Synthesis

Serves as a halogenated aromatic raw material for further functional group transformations and complex molecule synthesis.

④ New Materials and Electronic Chemicals Research & Development

The fluorinated aromatic structure shows application potential in functional materials and specialty chemical research.

5. Product Characteristics and Advantages

① High-Value Fluorinated Structure

The CF₃ structure is an important functional group in modern high-end fine chemicals.

② Good Synthetic Application Value

The bromine and fluorine groups together provide diverse reaction pathways.

③ Clear International Market Demand

Primarily serves pharmaceutical, agrochemical, and fine chemical industry chain customers.

6. Distinctions from Related Products

① vs. 2-Bromo-5-fluorobenzotrifluoride

Both are brominated fluorinated trifluoromethylbenzenes, but differ in substitution position, which affects downstream synthesis routes and target molecule design.

② vs. 5-Chloro-2-nitrobenzotrifluoride

This product is more oriented toward halogen coupling reaction applications, while the nitro product is more oriented toward nitro functional group transformation routes.

③ vs. Conventional Bromobenzenes

This product features CF₃ and F structures, offering higher added value and broader application scope.

7. Russian Market Procurement Considerations

Customers typically focus on the following:

-Product Purity;

-GC Purity;

-Moisture Content;

Single Impurity Control;

-Appearance and Color;

-Packaging Stability;

-Technical Documentation including COA, TDS, SDS;

-Stable Supply Capability.

8. Product Supply Advantages

-Fluorinated Aromatic Intermediate Supply Capability;

-Supports International Customer Procurement Requirements;

-Provides Quality Documentation and Technical Data;

-Serves Pharmaceutical, Agrochemical, and New Materials Industry Chain Customers.

9. Frequently Asked Questions (FAQ)

Q: What are the main applications of 5-Bromo-2-fluorobenzotrifluoride?

A: It is mainly used in fluorinated pharmaceutical intermediates, pesticide intermediates, and fine organic synthesis.

Q: Why do CF₃-containing products have high value?

A: The CF₃ group improves molecular stability, electronic properties, and hydrophobicity, making it an important structural unit in modern fluorinated chemicals.

Q: What documentation is typically required for procurement of this product?

A: COA, TDS, SDS, packaging information, and shipping documentation are typically required.