5-Chloro-2-nitrobenzotrifluoride CAS 320-51-4, for Fluorinated Pharmaceutical Intermediates, Pesticide Intermediates, and Fine Chemical Synthesis Applications

1. Product Overview

5-Chloro-2-nitrobenzotrifluoride is an important fluorinated aromatic fine chemical belonging to the class of chlorinated nitro trifluoromethylbenzene compounds.

This product contains trifluoromethyl (CF₃), chloro, and nitro (NO₂) functional groups in its molecular structure, offering strong electron-modulating capability and further chemical transformation potential. It serves as a key intermediate in fluorinated pharmaceuticals, pesticides, and specialty organic synthesis.

2. Product Specifications

Product Name: 5-Chloro-2-nitrobenzotrifluoride

English Name: 5-Chloro-2-nitrobenzotrifluoride

CAS No.: 320-51-4

Product Category: Fluorinated Aromatic Compound / Fine Chemical Intermediate

Structural Type: Chlorinated Nitro Trifluoromethyl Aromatic Compound

Application Areas: Pharmaceutical Intermediates, Pesticide Intermediates, Functional Chemicals

3. Product Structural Characteristics

① Trifluoromethyl (CF₃) Structure

The CF₃ group enhances electron-withdrawing capacity, hydrophobicity, and chemical stability, serving as an important structural unit in modern fluorinated pharmaceuticals and agrochemicals.

② Nitro (NO₂) Functional Group

The nitro group exhibits strong reactivity and can be further converted into other functional structures through reduction, substitution, and other reactions.

③ Chloro Substituent Structure

The chlorine atom provides a reactive site for subsequent coupling and substitution reactions, facilitating the construction of complex organic molecules.

4. Main Application Areas

① Fluorinated Pharmaceutical Intermediates

Used in fluorinated drug molecule design and aromatic structure construction.

② Pesticide Intermediates

Used in the research and development of fluorinated herbicides, insecticides, and plant protection products.

③ Fine Chemical Synthesis

Serves as an important aromatic building block for further functional group transformations.

④ New Materials and Research Applications

Used in fluorinated functional molecules and specialty material research.

5. Product Characteristics and Advantages

① High Value-Added CF₃ Structure

The trifluoromethyl group is an important functional group in high-end fine chemicals.

② Multi-Functional Group Combination Advantage

Combining CF₃, Cl, and NO₂ structures offers significant synthetic development value.

③ Broad Downstream Application Scope

Covers multiple industry chains including pharmaceuticals, agrochemicals, and new materials.

6. Distinctions from Related Products

① vs. 2,4-Dichloro-3,5-dinitrobenzotrifluoride

Both are fluorinated nitro aromatic compounds, but this product has a simpler structure, making it more suitable as a single aromatic synthesis building block.

② vs. Benzotrifluoride

Benzotrifluoride is a basic fluorinated raw material; this product has additional nitro and chloro groups, offering higher reaction value.

③ vs. Conventional Chloronitrobenzenes

The CF₃ structure imparts superior electronic properties and application value.

7. Russian Market Procurement Considerations

Customers typically focus on the following:

-Product Purity;

-GC Purity;

-Moisture Content;

-Single Impurity Control;

-Appearance;

-Packaging Stability;

-Technical Documentation including COA, TDS, SDS;

-Long-Term Supply Capability.

8. Product Supply Advantages

-Fluorinated Aromatic Intermediate Supply Capability;

-Supports International Customer Procurement Requirements;

-Provides Complete Quality Documentation;

-Serves Pharmaceutical, Agrochemical, and Fine Chemical Customers.

9. Frequently Asked Questions (FAQ)

Q: What are the main applications of 5-Chloro-2-nitrobenzotrifluoride?

A: It is mainly used in fluorinated pharmaceutical intermediates, pesticide intermediates, and fine organic synthesis.

Q: Why do CF₃-containing products have high value?

A: The CF₃ group improves molecular stability, electronic properties, and hydrophobicity, making it an important structural unit in modern fluorinated chemicals.

Q: What documentation is typically required for procurement of this product?

A: COA, TDS, SDS, packaging information, and shipping documentation are typically required.