4-(Trifluoromethylthio)phenol (CAS 371-72-8) is used in fluorinated fine chemicals, pharmaceutical intermediates, and pesticide intermediates.

1. Product Overview

4-(Trifluoromethylthio)phenol is an important fluorinated aromatic fine chemical, belonging to the sulfur- and fluorine-containing aromatic intermediates.

Its structure contains both a phenolic hydroxyl (-OH) group and a trifluoromethylthio (SCF₃) functional group, combining the stability of a fluorinated structure, the reactivity of a sulfur-containing group, and the modifiability of aromatic compounds. It is a crucial synthetic intermediate in the pharmaceutical, pesticide, and fine chemical industries.

2. Product Specifications

Product Name:
4-(Trifluoromethylthio)phenol
CAS Number: 371-72-8
Product Category: Fluorinated Aromatic Compounds / Sulfur- and Fluorine-Containing Intermediates
Structure Type: 4-Trifluoromethylthiophenol
Applications: Pharmaceutical intermediates, pesticide intermediates, functional chemicals

3. Product Structure Characteristics

① The trifluoromethylthio (SCF₃) structure
combines the characteristics of fluorine and sulfur elements, improving the electronic properties, lipophilicity, and stability of molecules. It is an important functional structure in high-end fluorinated chemicals in recent years.

② The phenolic hydroxyl (-OH) structure
exhibits good reactivity, allowing for etherification, esterification, and other functional group transformations.

③ The para-substituted aromatic structure, with its
regular structure, is advantageous for use as a building block in fine chemical synthesis.

4. Main application areas

① Fluorine-containing pharmaceutical intermediates
are used in the design of fluorine-containing drug molecules and can serve as aromatic functional structural units.

② The SCF₃ structure of pesticide intermediates
has important value in modern pesticide research and development and can be used in the development of fluorine-containing agrochemical products.

③ Fine chemical synthesis
is used for the synthesis of special aromatic compounds, functional molecules, and customized chemicals.

④ New material research and development
: Fluorine- and sulfur-containing structures can be used in the research of functional materials and specialty chemicals.

5. Product Features and Advantages

① The SCF₃ functional group is of high value;
the trifluoromethylthio group is an important structural unit in high-end fluorinated fine chemicals.

② It possesses a rich combination of functional groups
, exhibiting both SCF₃ and OH structures, demonstrating strong potential for further development.

③ Its application directions are clearly defined,
covering multiple high-value-added fields such as pharmaceuticals, agrochemicals, and new materials.

6. Differences from related products

① p-Trifluoromethylthiophenol and p-fluorotrifluorotoluene:
p-fluorotrifluorotoluene mainly provides the F/CF₃ structure, while this product adds sulfur and hydroxyl groups, resulting in different reactivity and applications.

② p-Trifluoromethylthiophenol and 4-fluoro-3-trifluoromethylphenol
are both fluorinated phenols, but the SCF₃ structure has more unique electronic and hydrophobic properties.

③ Compared to ordinary phenol products,
this product has a fluorinated and sulfur-containing structure, making it more valuable for applications.

7. Key Considerations for Procurement in the Russian Market

Customer focus on:
- Product purity;
- GC content;
- Moisture content;
- Single impurity control;
- Appearance and color;
- Packaging stability;
- COA, TDS, and SDS documentation;
- Long-term supply capability.

8. Product Supply Advantages

- Supply capability of fluorinated aromatic intermediates;
- Support for international customer procurement needs;
- Provision of complete quality documentation;
- Service to pharmaceutical, agrochemical, and fine chemical customers.

9. FAQ

Q: What are the main applications of p-trifluoromethylthiophenol?
A: Mainly used in the synthesis of fluorinated pharmaceutical intermediates, pesticide intermediates, and fine chemicals.

Q: Why is the SCF₃ structure highly valuable?
A: SCF₃ can improve the electronic properties, stability, and lipid solubility of molecules, making it an important structure for modern fluorinated chemical research and development.

Q: What documents are needed to purchase this product?
A: Typically, a Certificate of Authorization (COA), Test Data Sheet (TDS), SDS, packaging information, and shipping documents are required.