3,5-Bis(trifluoromethyl)bromobenzene CAS 328-70-1, for Fluorinated Pharmaceutical Intermediates, Pesticide Intermediates, and Fine Chemical Synthesis Applications

1. Product Overview

3,5-Bis(trifluoromethyl)bromobenzene is an important fluorinated aromatic fine chemical, belonging to the category of high-value polyfluorinated aromatic intermediates.

This product contains two trifluoromethyl (CF₃) groups and one bromine substituent, offering strong electron-withdrawing capability, excellent chemical stability, and good subsequent reactivity. It serves as an important synthetic building block in pharmaceuticals, pesticides, electronic chemicals, and specialty materials.

2. Product Specifications

Product Name: 3,5-Bis(trifluoromethyl)bromobenzene

English Name: 3,5-Bis(trifluoromethyl)bromobenzene

CAS No.: 328-70-1

Product Category: Fluorinated Aromatic Compound / Fine Chemical Intermediate

Chemical Formula: C₈H₃BrF₆

Application Areas: Pharmaceutical Intermediates, Pesticide Intermediates, Specialty Organic Synthesis

3. Product Structural Characteristics

① Bis(trifluoromethyl) Structure

The two CF₃ groups significantly enhance molecular electron-withdrawing capability and hydrophobic properties, serving as important structural units in modern fluorinated pharmaceuticals and functional materials.

② Bromine Substituent Structure

The bromine atom offers good reactivity for further construction of complex aromatic molecules through Suzuki coupling, metal-catalyzed coupling, and other reactions.

③ Highly Fluorinated Aromatic Structure

The polyfluorinated structure imparts enhanced stability and special physicochemical properties.

4. Main Application Areas

① Fluorinated Pharmaceutical Intermediates

Used in the structural construction of fluorinated drug molecules, serving as a commonly used aromatic synthetic building block in pharmaceutical research and development.

② Pesticide Intermediates

Used in the development of novel fluorinated herbicides, insecticides, and functional agrochemical products.

③ Fine Chemical Synthesis

Serves as a high-value aromatic raw material for the synthesis of complex organic molecules.

④ New Materials and Electronic Chemicals Research & Development

The bis-CF₃ structure can be used for functional molecule design and specialty material research.

5. Product Characteristics and Advantages

① High Fluorine Content and High Added Value

The two CF₃ groups give the product significant market value, classifying it as a high-end fluorinated intermediate.

② Outstanding Chemical Reaction Platform Value

The bromine group facilitates further coupling reactions, enabling various downstream structural developments.

③ Clear International Market Applications

Primarily serves pharmaceutical, agrochemical, and fine chemical customers.

6. Distinctions from Related Products

① vs. 2-Bromo-5-fluorobenzotrifluoride

Both are fluorinated brominated aromatic compounds, but 3,5-bis(trifluoromethyl)bromobenzene contains two CF₃ groups, offering higher fluorine content and more pronounced electronic effects.

② vs. Benzotrifluoride

Benzotrifluoride is a basic fluorinated raw material; this product has a bis-CF₃ structure with higher application value.

③ vs. Conventional Bromobenzenes

This product offers significant fluorinated structural advantages, making it more suitable for high-end synthesis applications.

7. Russian Market Procurement Considerations

Customers typically focus on the following:

-Product Purity;

-GC Purity;

-Moisture Content;

-Single Impurity Control;

-Appearance and Packaging Stability;

-Technical Documentation including COA, TDS, SDS;

-Long-Term Supply Capability.

8. Product Supply Advantages

-High-Value Fluorinated Aromatic Intermediate Supply Capability;

-Supports International Customer Procurement Requirements;

-Provides Quality Documentation and Technical Data;

-Serves Pharmaceutical, Agrochemical, and New Materials Industry Chains.

9. Frequently Asked Questions (FAQ)

Q: What are the main application areas of 3,5-Bis(trifluoromethyl)bromobenzene?

A: It is mainly used in fluorinated pharmaceutical intermediates, pesticide intermediates, fine chemicals, and specialty materials research and development.

Q: Why do bis-CF₃ structure products have high value?

A: The CF₃ structure improves molecular electronic properties, stability, and hydrophobicity, serving as an important structural unit in high-end fluorinated chemicals.

Q: What documentation is typically required for procurement of this product?

A: COA, TDS, SDS, packaging information, and shipping documentation are typically required.